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Nasri Nesnas

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Chemistry Department

Florida Institute of Technology

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II. Total Synthesis of CP-263,114

   While this pentacyclic structures has attracted the attention of most leading synthetic chemists since its isolation in 1997 from Fungus Twigs in Texas, we are interested in yet another approach at the construction of this unique type of natural product.  Our approach involves the  synthesis of two independent fragments to be attached at a later stage.  The methodology for the final attachments is currently underway using a truncated version of 1 serving as a model compound. 

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